Enhanced Activities of Blood Thiamine Diphosphatase and Monophosphatase in Alzheimer's Disease

BACKGROUND: Thiamine metabolites and activities of thiamine-dependent enzymes are impaired in Alzheimer’s disease (AD). OBJECTIVE: To clarify the mechanism for the reduction of thiamine diphosphate (TDP), an active form of thiamine and critical coenzyme of glucose metabolism, in AD. METHODS: Forty-f...

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Detalles Bibliográficos
Autores principales: Pan, Xiaoli, Sang, Shaoming, Fei, Guoqiang, Jin, Lirong, Liu, Huimin, Wang, Zhiliang, Wang, Hui, Zhong, Chunjiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218390/
https://www.ncbi.nlm.nih.gov/pubmed/28060825
http://dx.doi.org/10.1371/journal.pone.0167273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218390/
https://www.ncbi.nlm.nih.gov/pubmed/28060825
http://dx.doi.org/10.1371/journal.pone.0167273

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