The TIR Homologue Lies near Resistance Genes in Staphylococcus aureus, Coupling Modulation of Virulence and Antimicrobial Susceptibility

Toll/interleukin-1 receptor (TIR) domains in Toll-like receptors are essential for initiating and propagating the eukaryotic innate immune signaling cascade. Here, we investigate TirS, a Staphylococcus aureus TIR mimic that is part of a novel bacterial invasion mechanism. Its ectopic expression in e...

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Detalles Bibliográficos
Autores principales: Patot, Sabine, RC Imbert, Paul, Baude, Jessica, Martins Simões, Patricia, Campergue, Jean-Baptiste, Louche, Arthur, Nijland, Reindert, Bès, Michèle, Tristan, Anne, Laurent, Frédéric, Fischer, Adrien, Schrenzel, Jacques, Vandenesch, François, P Salcedo, Suzana, François, Patrice, Lina, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218399/
https://www.ncbi.nlm.nih.gov/pubmed/28060920
http://dx.doi.org/10.1371/journal.ppat.1006092

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