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Performance of (89)Zr-Labeled-Rituximab-PET as an Imaging Biomarker to Assess CD20 Targeting: A Pilot Study in Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma

PURPOSE: Treatment of patients with diffuse large B cell lymphoma (DLBCL) includes rituximab, an anti-CD20 monoclonal antibody (mAb). Insufficient tumor targeting might cause therapy failure. Tumor uptake of (89)Zirconium ((89)Zr)-mAb is a potential imaging biomarker for tumor targeting, since it de...

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Detalles Bibliográficos
Autores principales:	Jauw, Yvonne W. S., Zijlstra, Josée M., de Jong, Daphne, Vugts, Danielle J., Zweegman, Sonja, Hoekstra, Otto S., van Dongen, Guus A. M. S., Huisman, Marc C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218417/ https://www.ncbi.nlm.nih.gov/pubmed/28060891 http://dx.doi.org/10.1371/journal.pone.0169828

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