Cargando…

Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama

Synanthropic wild mammals can be important hosts for many vector-borne zoonotic pathogens. The aim of this study was determine the exposure of synanthropic mammals to two types of tick-borne pathogens in Panama, spotted fever group Rickettsia (SFGR) and Borrelia relapsing fever (RF) spirochetes. One...

Descripción completa

Detalles Bibliográficos
Autores principales: Bermúdez, Sergio E., Gottdenker, Nicole, Krishnvajhala, Aparna, Fox, Amy, Wilder, Hannah K., González, Kadir, Smith, Diorene, López, Marielena, Perea, Milixa, Rigg, Chystrie, Montilla, Santiago, Calzada, José E., Saldaña, Azael, Caballero, Carlos M., Lopez, Job E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218486/
https://www.ncbi.nlm.nih.gov/pubmed/28060928
http://dx.doi.org/10.1371/journal.pone.0169047
_version_ 1782492290703425536
author Bermúdez, Sergio E.
Gottdenker, Nicole
Krishnvajhala, Aparna
Fox, Amy
Wilder, Hannah K.
González, Kadir
Smith, Diorene
López, Marielena
Perea, Milixa
Rigg, Chystrie
Montilla, Santiago
Calzada, José E.
Saldaña, Azael
Caballero, Carlos M.
Lopez, Job E.
author_facet Bermúdez, Sergio E.
Gottdenker, Nicole
Krishnvajhala, Aparna
Fox, Amy
Wilder, Hannah K.
González, Kadir
Smith, Diorene
López, Marielena
Perea, Milixa
Rigg, Chystrie
Montilla, Santiago
Calzada, José E.
Saldaña, Azael
Caballero, Carlos M.
Lopez, Job E.
author_sort Bermúdez, Sergio E.
collection PubMed
description Synanthropic wild mammals can be important hosts for many vector-borne zoonotic pathogens. The aim of this study was determine the exposure of synanthropic mammals to two types of tick-borne pathogens in Panama, spotted fever group Rickettsia (SFGR) and Borrelia relapsing fever (RF) spirochetes. One hundred and thirty-one wild mammals were evaluated, including two gray foxes, two crab-eating foxes (from zoos), four coyotes, 62 opossum and 63 spiny rats captured close to rural towns. To evaluate exposure to SFGR, serum samples from the animals were tested by indirect immunofluorescence assay (IFA) using Rickettsia rickettsii and Candidatus Rickettsia amblyommii antigen. Immunoblotting was performed using Borrelia turicatae protein lysates and rGlpQ, to assess infection caused by RF spirochetes. One coyote (25%) and 27 (43%) opossums showed seroreactivity to SFGR. Of these opossums, 11 were seroreactive to C. R. amblyommii. Serological reactivity was not detected to B. turicatae in mammal samples. These findings may reflect a potential role of both mammals in the ecology of tick-borne pathogens in Panama.
format Online
Article
Text
id pubmed-5218486
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-52184862017-01-19 Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama Bermúdez, Sergio E. Gottdenker, Nicole Krishnvajhala, Aparna Fox, Amy Wilder, Hannah K. González, Kadir Smith, Diorene López, Marielena Perea, Milixa Rigg, Chystrie Montilla, Santiago Calzada, José E. Saldaña, Azael Caballero, Carlos M. Lopez, Job E. PLoS One Research Article Synanthropic wild mammals can be important hosts for many vector-borne zoonotic pathogens. The aim of this study was determine the exposure of synanthropic mammals to two types of tick-borne pathogens in Panama, spotted fever group Rickettsia (SFGR) and Borrelia relapsing fever (RF) spirochetes. One hundred and thirty-one wild mammals were evaluated, including two gray foxes, two crab-eating foxes (from zoos), four coyotes, 62 opossum and 63 spiny rats captured close to rural towns. To evaluate exposure to SFGR, serum samples from the animals were tested by indirect immunofluorescence assay (IFA) using Rickettsia rickettsii and Candidatus Rickettsia amblyommii antigen. Immunoblotting was performed using Borrelia turicatae protein lysates and rGlpQ, to assess infection caused by RF spirochetes. One coyote (25%) and 27 (43%) opossums showed seroreactivity to SFGR. Of these opossums, 11 were seroreactive to C. R. amblyommii. Serological reactivity was not detected to B. turicatae in mammal samples. These findings may reflect a potential role of both mammals in the ecology of tick-borne pathogens in Panama. Public Library of Science 2017-01-06 /pmc/articles/PMC5218486/ /pubmed/28060928 http://dx.doi.org/10.1371/journal.pone.0169047 Text en © 2017 Bermúdez et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Bermúdez, Sergio E.
Gottdenker, Nicole
Krishnvajhala, Aparna
Fox, Amy
Wilder, Hannah K.
González, Kadir
Smith, Diorene
López, Marielena
Perea, Milixa
Rigg, Chystrie
Montilla, Santiago
Calzada, José E.
Saldaña, Azael
Caballero, Carlos M.
Lopez, Job E.
Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama
title Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama
title_full Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama
title_fullStr Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama
title_full_unstemmed Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama
title_short Synanthropic Mammals as Potential Hosts of Tick-Borne Pathogens in Panama
title_sort synanthropic mammals as potential hosts of tick-borne pathogens in panama
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218486/
https://www.ncbi.nlm.nih.gov/pubmed/28060928
http://dx.doi.org/10.1371/journal.pone.0169047
work_keys_str_mv AT bermudezsergioe synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT gottdenkernicole synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT krishnvajhalaaparna synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT foxamy synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT wilderhannahk synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT gonzalezkadir synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT smithdiorene synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT lopezmarielena synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT pereamilixa synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT riggchystrie synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT montillasantiago synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT calzadajosee synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT saldanaazael synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT caballerocarlosm synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama
AT lopezjobe synanthropicmammalsaspotentialhostsoftickbornepathogensinpanama