Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones

Our previous paper (Wilkinson et al, 2016) used high-resolution cryo-electron microscopy to solve the structure of the Escherichia coli RecBCD complex, which acts in both the repair of double-stranded DNA breaks and the degradation of bacteriophage DNA. To counteract the latter activity, bacteriopha...

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Detalles Bibliográficos
Autores principales: Wilkinson, Martin, Troman, Lucy, Wan Nur Ismah, Wan AK, Chaban, Yuriy, Avison, Matthew B, Dillingham, Mark S, Wigley, Dale B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218532/
https://www.ncbi.nlm.nih.gov/pubmed/28009252
http://dx.doi.org/10.7554/eLife.22963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218532/
https://www.ncbi.nlm.nih.gov/pubmed/28009252
http://dx.doi.org/10.7554/eLife.22963

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