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When your cap matters: structural insights into self vs non-self recognition of 5′ RNA by immunomodulatory host proteins
Cytosolic recognition of viral RNA is important for host innate immune responses. Differential recognition of self vs non-self RNA is a considerable challenge as the inability to differentiate may trigger aberrant immune responses. Recent work identified the composition of the RNA 5′, including the...
Autores principales: | Leung, Daisy W, Amarasinghe, Gaya K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218996/ https://www.ncbi.nlm.nih.gov/pubmed/26916433 http://dx.doi.org/10.1016/j.sbi.2016.02.001 |
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