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New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity

Betulin 1 and its semisynthetic derivatives exhibit a cytotoxic activity toward various cancer cell lines. These compounds are a promising and potential anticancer candidates. A series of betulin derivatives was prepared and tested for the antiproliferative activity in vitro against T47D breast canc...

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Detalles Bibliográficos
Autores principales: Bębenek, Ewa, Kadela-Tomanek, Monika, Chrobak, Elwira, Wietrzyk, Joanna, Sadowska, Joanna, Boryczka, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219024/
https://www.ncbi.nlm.nih.gov/pubmed/28111514
http://dx.doi.org/10.1007/s00044-016-1713-9