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New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity
Betulin 1 and its semisynthetic derivatives exhibit a cytotoxic activity toward various cancer cell lines. These compounds are a promising and potential anticancer candidates. A series of betulin derivatives was prepared and tested for the antiproliferative activity in vitro against T47D breast canc...
Autores principales: | Bębenek, Ewa, Kadela-Tomanek, Monika, Chrobak, Elwira, Wietrzyk, Joanna, Sadowska, Joanna, Boryczka, Stanisław |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219024/ https://www.ncbi.nlm.nih.gov/pubmed/28111514 http://dx.doi.org/10.1007/s00044-016-1713-9 |
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