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Utility of the succinate:fumarate ratio for assessing SDH dysfunction in different tumor types()

OBJECTIVE: Mutations of genes encoding the four subunits of succinate dehydrogenase (SDH) have been associated with pheochromocytoma and paraganglioma (PPGLs), gastrointestinal stromal tumors (GISTs) and renal cell carcinomas (RCCs). These tumors have not been characterized in a way that reflects se...

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Detalles Bibliográficos
Autores principales:	Kim, Edward, Wright, Michael JP., Sioson, Loretta, Novos, Talia, Gill, Anthony J., Benn, Diana E., White, Christopher, Dwight, Trisha, Clifton-Bligh, Roderick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219629/ https://www.ncbi.nlm.nih.gov/pubmed/28070496 http://dx.doi.org/10.1016/j.ymgmr.2016.12.006

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