Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?

Severe asthma is a major health concern. The allergic (IgE-mediated) form of asthma is well known from a pathogenic viewpoint. We searched the available literature to identify which allergens are most frequently associated with severe, refractory or life threatening asthma. According to the results,...

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Autores principales: Lombardi, Carlo, Savi, Eleonora, Ridolo, Erminia, Passalacqua, Giovanni, Canonica, Giorgio Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219672/
https://www.ncbi.nlm.nih.gov/pubmed/28101292
http://dx.doi.org/10.1186/s40413-016-0138-8
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author Lombardi, Carlo
Savi, Eleonora
Ridolo, Erminia
Passalacqua, Giovanni
Canonica, Giorgio Walter
author_facet Lombardi, Carlo
Savi, Eleonora
Ridolo, Erminia
Passalacqua, Giovanni
Canonica, Giorgio Walter
author_sort Lombardi, Carlo
collection PubMed
description Severe asthma is a major health concern. The allergic (IgE-mediated) form of asthma is well known from a pathogenic viewpoint. We searched the available literature to identify which allergens are most frequently associated with severe, refractory or life threatening asthma. According to the results, molds, pet dander, cockroach and ragweed were more frequently responsible for severe asthma. Thunderstorm asthma, in addition, represents a special association between allergic sensitization and an external climatic factor. A detailed knowledge of the most harmful allergens is mandatory for an appropriate diagnostic and preventive approach.
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spelling pubmed-52196722017-01-18 Is allergic sensitization relevant in severe asthma? Which allergens may be culprit? Lombardi, Carlo Savi, Eleonora Ridolo, Erminia Passalacqua, Giovanni Canonica, Giorgio Walter World Allergy Organ J Review Severe asthma is a major health concern. The allergic (IgE-mediated) form of asthma is well known from a pathogenic viewpoint. We searched the available literature to identify which allergens are most frequently associated with severe, refractory or life threatening asthma. According to the results, molds, pet dander, cockroach and ragweed were more frequently responsible for severe asthma. Thunderstorm asthma, in addition, represents a special association between allergic sensitization and an external climatic factor. A detailed knowledge of the most harmful allergens is mandatory for an appropriate diagnostic and preventive approach. BioMed Central 2017-01-06 /pmc/articles/PMC5219672/ /pubmed/28101292 http://dx.doi.org/10.1186/s40413-016-0138-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Lombardi, Carlo
Savi, Eleonora
Ridolo, Erminia
Passalacqua, Giovanni
Canonica, Giorgio Walter
Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?
title Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?
title_full Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?
title_fullStr Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?
title_full_unstemmed Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?
title_short Is allergic sensitization relevant in severe asthma? Which allergens may be culprit?
title_sort is allergic sensitization relevant in severe asthma? which allergens may be culprit?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219672/
https://www.ncbi.nlm.nih.gov/pubmed/28101292
http://dx.doi.org/10.1186/s40413-016-0138-8
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