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Pyviko: an automated Python tool to design gene knockouts in complex viruses with overlapping genes
BACKGROUND: Gene knockouts are a common tool used to study gene function in various organisms. However, designing gene knockouts is complicated in viruses, which frequently contain sequences that code for multiple overlapping genes. Designing mutants that can be traced by the creation of new or elim...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219722/ https://www.ncbi.nlm.nih.gov/pubmed/28061810 http://dx.doi.org/10.1186/s12866-016-0920-3 |