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Modular combinatorial binding among human trans-acting factors reveals direct and indirect factor binding

BACKGROUND: The combinatorial binding of trans-acting factors (TFs) to the DNA is critical to the spatial and temporal specificity of gene regulation. For certain regulatory regions, more than one regulatory module (set of TFs that bind together) are combined to achieve context-specific gene regulat...

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Detalles Bibliográficos
Autores principales: Guo, Yuchun, Gifford, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219757/
https://www.ncbi.nlm.nih.gov/pubmed/28061806
http://dx.doi.org/10.1186/s12864-016-3434-3