The nature and nurture of cell heterogeneity: accounting for macrophage gene-environment interactions with single-cell RNA-Seq

BACKGROUND: Single-cell RNA-Seq can be a valuable and unbiased tool to dissect cellular heterogeneity, despite the transcriptome’s limitations in describing higher functional phenotypes and protein events. Perhaps the most important shortfall with transcriptomic ‘snapshots’ of cell populations is th...

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Detalles Bibliográficos
Autores principales: Wills, Quin F., Mellado-Gomez, Esther, Nolan, Rory, Warner, Damien, Sharma, Eshita, Broxholme, John, Wright, Benjamin, Lockstone, Helen, James, William, Lynch, Mark, Gonzales, Michael, West, Jay, Leyrat, Anne, Padilla-Parra, Sergi, Filippi, Sarah, Holmes, Chris, Moore, Michael D., Bowden, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219790/
https://www.ncbi.nlm.nih.gov/pubmed/28061811
http://dx.doi.org/10.1186/s12864-016-3445-0

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