Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium

Aberrant Wnt signaling within breast cancer is associated with poor prognosis, but regulation of this pathway in breast tissue remains poorly understood and the consequences of immediate or long-term dysregulation remain elusive. The exact contribution of the Wnt-regulating proteins adenomatous poly...

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Detalles Bibliográficos
Autores principales: Daly, C S, Shaw, P, Ordonez, L D, Williams, G T, Quist, J, Grigoriadis, A, Van Es, J H, Clevers, H, Clarke, A R, Reed, K R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219933/
https://www.ncbi.nlm.nih.gov/pubmed/27694902
http://dx.doi.org/10.1038/onc.2016.342

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