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Enhancement of Gastric Ulcer Healing and Angiogenesis by Hepatocyte Growth Factor Gene Mediated by Attenuated Salmonella in Rats

The present study developed an oral hepatocyte growth factor (HGF) gene therapy strategy for gastric ulcers treatment. An attenuated Salmonella typhimurium that stably expressed high HGF (named as TPH) was constructed, and the antiulcerogenic effect of TPH was evaluated in a rat model of gastric ulc...

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Detalles Bibliográficos
Autores principales: Ha, Xiaoqin, Peng, Junhua, Zhao, Hongbin, Deng, Zhiyun, Dong, Juzi, Fan, Hongyan, Zhao, Yong, Li, Bing, Feng, Qiangsheng, Yang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219983/
https://www.ncbi.nlm.nih.gov/pubmed/28049228
http://dx.doi.org/10.3346/jkms.2017.32.2.186