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ASIC1a mediates the drug resistance of human hepatocellular carcinoma via the Ca(2+)/PI3-kinase/AKT signaling pathway

Chemotherapy is the main treatment method of patients with advanced liver cancer. However, drug resistance is a serious problem in the treatment of hepatocellular carcinoma (HCC). Acid sensing ion channel 1a (ASIC1a) is a H(+)-gated cation channel; it mediates tumor cell migration and invasion, whic...

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Detalles Bibliográficos
Autores principales:	Zhang, Yihao, Zhang, Ting, Wu, Chao, Xia, Quan, Xu, Dujuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220138/ https://www.ncbi.nlm.nih.gov/pubmed/27918554 http://dx.doi.org/10.1038/labinvest.2016.127

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