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Proanthocyanidins potentiate hypothalamic leptin/STAT3 signalling and Pomc gene expression in rats with diet-induced obesity

OBJECTIVE: Dietary obesity is usually linked with hypothalamic leptin resistance, in which the primary impact is an interference in the homeostatic control of body weight and appetite. Notably, proanthocyanidins (PACs), which are the most abundant phenolic compounds present in human diet, modulate a...

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Detalles Bibliográficos
Autores principales:	Ibars, M, Ardid-Ruiz, A, Suárez, M, Muguerza, B, Bladé, C, Aragonès, G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220160/ https://www.ncbi.nlm.nih.gov/pubmed/27677620 http://dx.doi.org/10.1038/ijo.2016.169

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