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Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine
The data on the immunohistochemical analysis of conditional Notch ligand knockout mice is presented. Targeted deletion of Jag1, Dll1, Dll4, or Dll1 plus Dll4 in Lgr5(+ve) cells was induced by a Cre-mediated gene recombination, and differentiation or proliferation of the intestinal epithelial cells w...
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220229/ https://www.ncbi.nlm.nih.gov/pubmed/28124021 http://dx.doi.org/10.1016/j.dib.2016.12.045 |
| _version_ | 1782492586187948032 |
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| author | Nakata, Toru Shimizu, Hiromichi Nagata, Sayaka Ito, Go Fujii, Satoru Suzuki, Kohei Kawamoto, Ami Ishibashi, Fumiaki Kuno, Reiko Anzai, Sho Murano, Tatsuro Mizutani, Tomohiro Oshima, Shigeru Tsuchiya, Kiichiro Nakamura, Tetsuya Hozumi, Katsuto Watanabe, Mamoru Okamoto, Ryuichi |
| author_facet | Nakata, Toru Shimizu, Hiromichi Nagata, Sayaka Ito, Go Fujii, Satoru Suzuki, Kohei Kawamoto, Ami Ishibashi, Fumiaki Kuno, Reiko Anzai, Sho Murano, Tatsuro Mizutani, Tomohiro Oshima, Shigeru Tsuchiya, Kiichiro Nakamura, Tetsuya Hozumi, Katsuto Watanabe, Mamoru Okamoto, Ryuichi |
| author_sort | Nakata, Toru |
| collection | PubMed |
| description | The data on the immunohistochemical analysis of conditional Notch ligand knockout mice is presented. Targeted deletion of Jag1, Dll1, Dll4, or Dll1 plus Dll4 in Lgr5(+ve) cells was induced by a Cre-mediated gene recombination, and differentiation or proliferation of the intestinal epithelial cells was examined by immunohistochemistry. These data are the extension of the data presented and discussed in the paper entitled “Indispensable role of non-canonical Notch signaling in the proliferation of Apc-deficient intestinal tumors“ (Nakata et al., Submitted for publication) [1]. |
| format | Online Article Text |
| id | pubmed-5220229 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-52202292017-01-25 Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine Nakata, Toru Shimizu, Hiromichi Nagata, Sayaka Ito, Go Fujii, Satoru Suzuki, Kohei Kawamoto, Ami Ishibashi, Fumiaki Kuno, Reiko Anzai, Sho Murano, Tatsuro Mizutani, Tomohiro Oshima, Shigeru Tsuchiya, Kiichiro Nakamura, Tetsuya Hozumi, Katsuto Watanabe, Mamoru Okamoto, Ryuichi Data Brief Data Article The data on the immunohistochemical analysis of conditional Notch ligand knockout mice is presented. Targeted deletion of Jag1, Dll1, Dll4, or Dll1 plus Dll4 in Lgr5(+ve) cells was induced by a Cre-mediated gene recombination, and differentiation or proliferation of the intestinal epithelial cells was examined by immunohistochemistry. These data are the extension of the data presented and discussed in the paper entitled “Indispensable role of non-canonical Notch signaling in the proliferation of Apc-deficient intestinal tumors“ (Nakata et al., Submitted for publication) [1]. Elsevier 2016-12-29 /pmc/articles/PMC5220229/ /pubmed/28124021 http://dx.doi.org/10.1016/j.dib.2016.12.045 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Data Article Nakata, Toru Shimizu, Hiromichi Nagata, Sayaka Ito, Go Fujii, Satoru Suzuki, Kohei Kawamoto, Ami Ishibashi, Fumiaki Kuno, Reiko Anzai, Sho Murano, Tatsuro Mizutani, Tomohiro Oshima, Shigeru Tsuchiya, Kiichiro Nakamura, Tetsuya Hozumi, Katsuto Watanabe, Mamoru Okamoto, Ryuichi Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine |
| title | Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine |
| title_full | Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine |
| title_fullStr | Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine |
| title_full_unstemmed | Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine |
| title_short | Data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of Notch ligands in mouse intestine |
| title_sort | data showing proliferation and differentiation of intestinal epithelial cells under targeted depletion of notch ligands in mouse intestine |
| topic | Data Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220229/ https://www.ncbi.nlm.nih.gov/pubmed/28124021 http://dx.doi.org/10.1016/j.dib.2016.12.045 |
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