Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes

Serelaxin prevents endothelial dysfunction in the mouse aorta ex vivo and inhibits apoptosis in cardiomyocytes under acute hyperglycaemia. Less is known about the effects of serelaxin in an in vivo mouse model of diabetes. Therefore, we tested the hypothesis in streptozotocin (STZ)-treated mice that...

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Detalles Bibliográficos
Autores principales: Ng, Hooi Hooi, Leo, Chen Huei, Prakoso, Darnel, Qin, Chengxue, Ritchie, Rebecca H., Parry, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220363/
https://www.ncbi.nlm.nih.gov/pubmed/28067255
http://dx.doi.org/10.1038/srep39604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220363/
https://www.ncbi.nlm.nih.gov/pubmed/28067255
http://dx.doi.org/10.1038/srep39604

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