Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation

Pancreatic ductal adenocarcinoma (PDAC) is virtually therapy-resistant. As noninvasive lesions progress to malignancy, the precursor period provides a window for cancer therapies that can interfere with neoplastic progression. Thymoquinone (Tq), a major bioactive component of essential oil from Nige...

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Detalles Bibliográficos
Autores principales: Relles, Daniel, Chipitsyna, Galina I., Gong, Qiaoke, Yeo, Charles J., Arafat, Hwyda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220391/
https://www.ncbi.nlm.nih.gov/pubmed/28105374
http://dx.doi.org/10.1155/2016/1407840

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