The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches

Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the...

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Detalles Bibliográficos
Autores principales: Pandya, Pankita H., Murray, Mary E., Pollok, Karen E., Renbarger, Jamie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220497/
https://www.ncbi.nlm.nih.gov/pubmed/28116316
http://dx.doi.org/10.1155/2016/4273943
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author Pandya, Pankita H.
Murray, Mary E.
Pollok, Karen E.
Renbarger, Jamie L.
author_facet Pandya, Pankita H.
Murray, Mary E.
Pollok, Karen E.
Renbarger, Jamie L.
author_sort Pandya, Pankita H.
collection PubMed
description Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies.
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spelling pubmed-52204972017-01-23 The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches Pandya, Pankita H. Murray, Mary E. Pollok, Karen E. Renbarger, Jamie L. J Immunol Res Review Article Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies. Hindawi Publishing Corporation 2016 2016-12-26 /pmc/articles/PMC5220497/ /pubmed/28116316 http://dx.doi.org/10.1155/2016/4273943 Text en Copyright © 2016 Pankita H. Pandya et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Pandya, Pankita H.
Murray, Mary E.
Pollok, Karen E.
Renbarger, Jamie L.
The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
title The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
title_full The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
title_fullStr The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
title_full_unstemmed The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
title_short The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
title_sort immune system in cancer pathogenesis: potential therapeutic approaches
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220497/
https://www.ncbi.nlm.nih.gov/pubmed/28116316
http://dx.doi.org/10.1155/2016/4273943
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