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Simultaneous Determination of Bergapten, Imperatorin, Notopterol, and Isoimperatorin in Rat Plasma by High Performance Liquid Chromatography with Fluorescence Detection and Its Application to Pharmacokinetic and Excretion Study after Oral Administration of Notopterygium incisum Extract

A specific, sensitive, and reliable high performance liquid chromatography with fluorescence detection (HPLC-FLD) was first optimized and then used in the simultaneous quantification of bergapten, imperatorin, notopterol, and isoimperatorin in rat plasma using osthole as the internal standard. Liqui...

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Detalles Bibliográficos
Autores principales: Teye Azietaku, John, Yu, Xie-an, Li, Jin, Hao, Jia, Cao, Jun, An, Mingrui, Tan, Zhijing, Chang, Yan-xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220503/
https://www.ncbi.nlm.nih.gov/pubmed/28115935
http://dx.doi.org/10.1155/2016/9507246

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