The SGLT-2 Inhibitor Dapagliflozin Has a Therapeutic Effect on Atherosclerosis in Diabetic ApoE(−/−) Mice

Background. Our study aimed to observe the effect of sodium glucose cotransporter-2 (SGLT2) inhibitor dapagliflozin on diabetic atherosclerosis and investigate the subsequent mechanism. Methods. Aortic atherosclerosis was induced in streptozotocin induced diabetic ApoE(−/−) mice by feeding with high...

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Detalles Bibliográficos
Autores principales: Leng, Weiling, Ouyang, Xinshou, Lei, Xiaotian, Wu, Mingxia, Chen, Liu, Wu, Qinan, Deng, Wuquan, Liang, Ziwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220517/
https://www.ncbi.nlm.nih.gov/pubmed/28104929
http://dx.doi.org/10.1155/2016/6305735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220517/
https://www.ncbi.nlm.nih.gov/pubmed/28104929
http://dx.doi.org/10.1155/2016/6305735

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