Sarcopenia and chemotherapy-mediated toxicity

This narrative review focuses on the role of sarcopenia and chemotherapy-induced toxicity in cancer patients. Consistent evidence shows that sarcopenia in cancer patients leads to decreased overall survival by influencing treatment discontinuation and dose reduction. Therefore, sarcopenia should be...

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Detalles Bibliográficos
Autores principales: Vega, Maria Cecília Monteiro Dela, Laviano, Alessandro, Pimentel, Gustavo Duarte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2016
Materias:
Medical Developments
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221390/
https://www.ncbi.nlm.nih.gov/pubmed/28076611
http://dx.doi.org/10.1590/S1679-45082016MD3740
Descripción
Sumario:This narrative review focuses on the role of sarcopenia and chemotherapy-induced toxicity in cancer patients. Consistent evidence shows that sarcopenia in cancer patients leads to decreased overall survival by influencing treatment discontinuation and dose reduction. Therefore, sarcopenia should be considered a robust prognostic factor of negative outcome as well as a determinant of increased healthcare costs.

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