Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin

We report a case of immunoglobulin G4 (IgG4)‐related lung disease presenting as a solitary pulmonary nodule with an irregular margin on computed tomography. The nodule showed a high standardized uptake value on positron emission tomography. A malignant pulmonary tumour could not be excluded. Middle...

Descripción completa

Detalles Bibliográficos
Autores principales: Okubo, Tetsuyuki, Oyamada, Yumiko, Kawada, Masaya, Kawarada, Yo, Kitashiro, Shuji, Okushiba, Shunichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221465/
https://www.ncbi.nlm.nih.gov/pubmed/28078088
http://dx.doi.org/10.1002/rcr2.208
_version_ 1782492818054316032
author Okubo, Tetsuyuki
Oyamada, Yumiko
Kawada, Masaya
Kawarada, Yo
Kitashiro, Shuji
Okushiba, Shunichi
author_facet Okubo, Tetsuyuki
Oyamada, Yumiko
Kawada, Masaya
Kawarada, Yo
Kitashiro, Shuji
Okushiba, Shunichi
author_sort Okubo, Tetsuyuki
collection PubMed
description We report a case of immunoglobulin G4 (IgG4)‐related lung disease presenting as a solitary pulmonary nodule with an irregular margin on computed tomography. The nodule showed a high standardized uptake value on positron emission tomography. A malignant pulmonary tumour could not be excluded. Middle lobectomy was performed. Histological analysis revealed marked lymphoplasmacytic infiltration and storiform fibrosis. Immunostaining indicated the presence of IgG4‐positive plasma cells. A definitive diagnosis of IgG4‐related disease was confirmed.
format Online
Article
Text
id pubmed-5221465
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher John Wiley & Sons, Ltd
record_format MEDLINE/PubMed
spelling pubmed-52214652017-01-11 Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin Okubo, Tetsuyuki Oyamada, Yumiko Kawada, Masaya Kawarada, Yo Kitashiro, Shuji Okushiba, Shunichi Respirol Case Rep Case Reports We report a case of immunoglobulin G4 (IgG4)‐related lung disease presenting as a solitary pulmonary nodule with an irregular margin on computed tomography. The nodule showed a high standardized uptake value on positron emission tomography. A malignant pulmonary tumour could not be excluded. Middle lobectomy was performed. Histological analysis revealed marked lymphoplasmacytic infiltration and storiform fibrosis. Immunostaining indicated the presence of IgG4‐positive plasma cells. A definitive diagnosis of IgG4‐related disease was confirmed. John Wiley & Sons, Ltd 2016-12-08 /pmc/articles/PMC5221465/ /pubmed/28078088 http://dx.doi.org/10.1002/rcr2.208 Text en © 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Okubo, Tetsuyuki
Oyamada, Yumiko
Kawada, Masaya
Kawarada, Yo
Kitashiro, Shuji
Okushiba, Shunichi
Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin
title Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin
title_full Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin
title_fullStr Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin
title_full_unstemmed Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin
title_short Immunoglobulin G4‐related disease presenting as a pulmonary nodule with an irregular margin
title_sort immunoglobulin g4‐related disease presenting as a pulmonary nodule with an irregular margin
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221465/
https://www.ncbi.nlm.nih.gov/pubmed/28078088
http://dx.doi.org/10.1002/rcr2.208
work_keys_str_mv AT okubotetsuyuki immunoglobuling4relateddiseasepresentingasapulmonarynodulewithanirregularmargin
AT oyamadayumiko immunoglobuling4relateddiseasepresentingasapulmonarynodulewithanirregularmargin
AT kawadamasaya immunoglobuling4relateddiseasepresentingasapulmonarynodulewithanirregularmargin
AT kawaradayo immunoglobuling4relateddiseasepresentingasapulmonarynodulewithanirregularmargin
AT kitashiroshuji immunoglobuling4relateddiseasepresentingasapulmonarynodulewithanirregularmargin
AT okushibashunichi immunoglobuling4relateddiseasepresentingasapulmonarynodulewithanirregularmargin

Ejemplares similares