Cargando…

Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore

Recruitment of spindle assembly checkpoint (SAC) proteins by an unattached kinetochore leads to SAC activation. This recruitment is licensed by the Mps1 kinase, which phosphorylates the kinetochore protein Spc105 at one or more of its six MELT repeats. Spc105 then recruits the Bub3-Bub1 and Mad1-Mad...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aravamudhan, Pavithra, Chen, Renjie, Roy, Babhrubahan, Sim, Janice, Joglekar, Ajit P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221577/ https://www.ncbi.nlm.nih.gov/pubmed/27170178 http://dx.doi.org/10.1091/mbc.E16-01-0007

Ejemplares similares

The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signaling
por: Aravamudhan, Pavithra, et al.
Publicado: (2015)

Delineating the contribution of Spc105-bound PP1 to spindle checkpoint silencing and kinetochore microtubule attachment regulation
por: Roy, Babhrubahan, et al.
Publicado: (2019)

BubR1 recruitment to the kinetochore via Bub1 enhances spindle assembly checkpoint signaling
por: Banerjee, Anand, et al.
Publicado: (2022)

Kre28–Spc105 interaction is essential for Spc105 loading at the kinetochore
por: Roy, Babhrubahan, et al.
Publicado: (2022)

The copy-number and varied strengths of MELT motifs in Spc105 balance the strength and responsiveness of the spindle assembly checkpoint
por: Roy, Babhrubahan, et al.
Publicado: (2020)

Kinetochore stretching inactivates the spindle assembly checkpoint
por: Uchida, Kazuhiko S.K., et al.
Publicado: (2009)

Spindle assembly checkpoint activation and silencing at kinetochores
por: Lara-Gonzalez, Pablo, et al.
Publicado: (2021)

Aberrantly segregating centromeres activate the spindle assembly checkpoint in budding yeast
Publicado: (1996)

Stu2 acts as a microtubule destabilizer in metaphase budding yeast spindles
por: Humphrey, Lauren, et al.
Publicado: (2018)

Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore
por: Griffis, Eric R., et al.
Publicado: (2007)

The Coordination of Centromere Replication, Spindle Formation, and Kinetochore–Microtubule Interaction in Budding Yeast
por: Liu, Hong, et al.
Publicado: (2008)

Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores
por: Dou, Zhen, et al.
Publicado: (2019)

A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint
por: Joglekar, Ajit P.
Publicado: (2016)

Simple centromere, complex kinetochore: linking spindle microtubules and centromeric DNA in budding yeast
por: Cheeseman, Iain M., et al.
Publicado: (2002)

Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast
Publicado: (1995)

Spindle Checkpoint Protein Xmad1 Recruits Xmad2 to Unattached Kinetochores
por: Chen, Rey-Huei, et al.
Publicado: (1998)

Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment
por: Krefman, Nathaniel I., et al.
Publicado: (2015)

Nanoscale structural organization and stoichiometry of the budding yeast kinetochore
por: Cieslinski, Konstanty, et al.
Publicado: (2023)

Kinetochore–microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint
por: Etemad, Banafsheh, et al.
Publicado: (2015)

The spindle position checkpoint in budding yeast: the motherly care of MEN
por: Piatti, Simonetta, et al.
Publicado: (2006)

Spindle checkpoint proteins and chromosome–microtubule attachment in budding yeast
por: Gillett, Emily S., et al.
Publicado: (2004)

Ndc10 is a platform for inner kinetochore assembly in budding yeast
por: Cho, Uhn-Soo, et al.
Publicado: (2011)

Budding Yeast Dma Proteins Control Septin Dynamics and the Spindle Position Checkpoint by Promoting the Recruitment of the Elm1 Kinase to the Bud Neck
por: Merlini, Laura, et al.
Publicado: (2012)

Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation
por: Montpetit, Ben, et al.
Publicado: (2006)

Phosphatase-regulated recruitment of the spindle- and kinetochore-associated (Ska) complex to kinetochores
por: Sivakumar, Sushama, et al.
Publicado: (2017)

Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity
por: Maresca, Thomas J., et al.
Publicado: (2009)

The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex
por: Chen, Chu, et al.
Publicado: (2023)

Bub1 Is a Fission Yeast Kinetochore Scaffold Protein, and Is Sufficient to Recruit other Spindle Checkpoint Proteins to Ectopic Sites on Chromosomes
por: Rischitor, Patricia E., et al.
Publicado: (2007)

The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond
por: Vader, Gerben, et al.
Publicado: (2008)

Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase
por: Kuijt, Timo E. F., et al.
Publicado: (2014)

Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores
por: Varma, Dileep, et al.
Publicado: (2013)

Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells
por: Tauchman, Eric C., et al.
Publicado: (2015)

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores
por: Isokane, Mayumi, et al.
Publicado: (2016)

Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores
por: Kim, Soonjoung, et al.
Publicado: (2015)

A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A
por: Hornung, Peter, et al.
Publicado: (2014)

Nup132 modulates meiotic spindle attachment in fission yeast by regulating kinetochore assembly
por: Yang, Hui-Ju, et al.
Publicado: (2015)

Analysis of kinesin motor function at budding yeast kinetochores
por: Tytell, Jessica D., et al.
Publicado: (2006)

Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint
por: London, Nitobe, et al.
Publicado: (2014)

MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling
por: Alfonso-Pérez, Tatiana, et al.
Publicado: (2019)

Spindle Assembly Checkpoint of Oocytes Depends on a Kinetochore Structure Determined by Cohesin in Meiosis I
por: Tachibana-Konwalski, Kikuë, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_asofptmvkpftem3j8bjm172kb0