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Kinesin-8 effects on mitotic microtubule dynamics contribute to spindle function in fission yeast

Kinesin-8 motor proteins destabilize microtubules. Their absence during cell division is associated with disorganized mitotic chromosome movements and chromosome loss. Despite recent work studying effects of kinesin-8s on microtubule dynamics, it remains unclear whether the kinesin-8 mitotic phenoty...

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Detalles Bibliográficos
Autores principales: Gergely, Zachary R., Crapo, Ammon, Hough, Loren E., McIntosh, J. Richard, Betterton, Meredith D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221583/
https://www.ncbi.nlm.nih.gov/pubmed/27146110
http://dx.doi.org/10.1091/mbc.E15-07-0505