Cargando…

Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau’s interaction with microtubules in axon-like processes

A current challenge of cell biology is to investigate molecular interactions in subcellular compartments of living cells to overcome the artificial character of in vitro studies. To dissect the interaction of the neuronal microtubule (MT)-associated protein tau with MTs in axon-like processes, we us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Niewidok, Benedikt, Igaev, Maxim, Sündermann, Frederik, Janning, Dennis, Bakota, Lidia, Brandt, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221586/ https://www.ncbi.nlm.nih.gov/pubmed/27582388 http://dx.doi.org/10.1091/mbc.E16-06-0402

Ejemplares similares

Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons
por: Janning, Dennis, et al.
Publicado: (2014)

Interplay between phosphorylation and palmitoylation mediates plasma membrane targeting and sorting of GAP43
por: Gauthier-Kemper, Anne, et al.
Publicado: (2014)

Super-resolution imaging and quantitative analysis of microtubule arrays in model neurons show that epothilone D increases the density but decreases the length and straightness of microtubules in axon-like processes()
por: Conze, Christian, et al.
Publicado: (2022)

Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport
por: Conze, Christian, et al.
Publicado: (2022)

Processes induced by tau expression in Sf9 cells have an axon-like microtubule organization
Publicado: (1991)

Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau
por: Brandt, Roland, et al.
Publicado: (2020)

Microtubule instability driven by longitudinal and lateral strain propagation
por: Igaev, Maxim, et al.
Publicado: (2020)

Single-molecule imaging reveals dynamic biphasic partition of RNA-binding proteins in stress granules
por: Niewidok, Benedikt, et al.
Publicado: (2018)

Bending-torsional elasticity and energetics of the plus-end microtubule tip
por: Igaev, Maxim, et al.
Publicado: (2022)

Tau reconstruction at CMS with a focus on high $ p_{T} $ taus
por: Bhattacharya, Soham
Publicado: (2019)

Acetylation: a new key to unlock tau’s role in neurodegeneration
por: Cook, Casey, et al.
Publicado: (2014)

Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease
por: Bakota, Lidia, et al.
Publicado: (2016)

Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit
por: Igaev, Maxim, et al.
Publicado: (2018)

An evolutionary roadmap to the microtubule-associated protein MAP Tau
por: Sündermann, Frederik, et al.
Publicado: (2016)

Performance of the DeepTau algorithm for the discrimination of taus against jets, electron, and muons
por: CMS Collaboration
Publicado: (2019)

Tau’s function and dysfunction in the brain: when small changes have big consequences
por: Portillo, Miguel, et al.
Publicado: (2023)

Polarisation des taus dans la réaction $e^{+}e^{-} \to \tau^{+}\tau^{-}$ au $Z^{0}$
por: Boillot, F
Publicado: (1987)

Physics with taus at CMS
por: Calabria, Cesare
Publicado: (2011)

Use of Taus in ATLAS
por: Hinchliffe, Ian
Publicado: (2002)

Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain
por: Sottejeau, Yoann, et al.
Publicado: (2015)

Tau Lysine Pseudomethylation Regulates Microtubule Binding and Enhances Prion-like Tau Aggregation
por: Xia, Yuxing, et al.
Publicado: (2023)

Microtubule-modulating Agents in the Fight Against Neurodegeneration: Will it ever Work?
por: Soliman, Ahmed, et al.
Publicado: (2022)

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner
por: Gauthier-Kemper, Anne, et al.
Publicado: (2011)

Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
por: Chung, Peter J., et al.
Publicado: (2016)

Higgs To Four Taus At ALEPH
por: Cranmer, Kyle
Publicado: (2010)

SUSY Searches with Taus at the LHC
por: Lyu, F.
Publicado: (2018)

Search for excited taus at LEP
por: Wang Yi Fang
Publicado: (1991)

Electron Vetoes and Taus at ATLAS
por: Bedikian, S
Publicado: (2011)

Higgs to Four Taus at ALEPH
por: Beacham, James
Publicado: (2010)

Tau’s Three-Repeat Domain and EFhd2 Co-incubation Leads to Increased Thioflavin Signal
por: Vega, Irving E., et al.
Publicado: (2018)

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative processes
por: Golovyashkina, Nataliya, et al.
Publicado: (2015)

Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase
por: Chen, Lizhen, et al.
Publicado: (2015)

The Evolution of Tau Phosphorylation and Interactions
por: Trushina, Nataliya I., et al.
Publicado: (2019)

$Z$ and $W$ Physics with Taus at the LHC
por: Ilten, Philip
Publicado: (2014)

Pékin : Atelier taus et charme
Publicado: (1996)

Higgs boson searches with taus in CMS
por: Bachtis, Michail
Publicado: (2011)

Search For New Physics With Taus at the LHC
por: Chierici, R
Publicado: (2004)

Prospects for Higgs search with Taus in the MSSM
por: Cavalli, D, et al.
Publicado: (1992)

Role of tau in the spatial organization of axonal microtubules: keeping parallel microtubules evenly distributed despite macromolecular crowding
por: Méphon-Gaspard, Alix, et al.
Publicado: (2016)

Motor axon navigation relies on Fidgetin-like 1–driven microtubule plus end dynamics
por: Fassier, Coralie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0q7vi578rh32novc52ibevmdfl