ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens

Rho kinases (ROCK1 and ROCK2) function downstream of the small GTPase RhoA to drive actomyosin cytoskeletal remodeling. It has often been believed that ROCK1 and ROCK2 may be functionally redundant, as they share a highly conserved kinase domain. However, in this study, we report differential functi...

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Detalles Bibliográficos
Autores principales: Priya, Rashmi, Liang, Xuan, Teo, Jessica L., Duszyc, Kinga, Yap, Alpha S., Gomez, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221615/
https://www.ncbi.nlm.nih.gov/pubmed/28035042
http://dx.doi.org/10.1091/mbc.E16-04-0262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221615/
https://www.ncbi.nlm.nih.gov/pubmed/28035042
http://dx.doi.org/10.1091/mbc.E16-04-0262

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