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Golgi enzymes do not cycle through the endoplasmic reticulum during protein secretion or mitosis
Golgi-specific sialyltransferase (ST) expressed as a chimera with the rapamycin-binding domain of mTOR, FRB, relocates to the endoplasmic reticulum (ER) in cells exposed to rapamycin that also express invariant chain (Ii)-FKBP in the ER. This result has been taken to indicate that Golgi-resident enz...
Autores principales: | Villeneuve, Julien, Duran, Juan, Scarpa, Margherita, Bassaganyas, Laia, Van Galen, Josse, Malhotra, Vivek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221618/ https://www.ncbi.nlm.nih.gov/pubmed/27807044 http://dx.doi.org/10.1091/mbc.E16-08-0560 |
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