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The pleckstrin-homology domain of dynamin is dispensable for membrane constriction and fission

Classical dynamins bind the plasma membrane–localized phosphatidylinositol-4,5-bisphosphate using the pleckstrin-homology domain (PHD) and engage in rapid membrane fission during synaptic vesicle recycling. This domain is conspicuously absent among extant bacterial and mitochondrial dynamins, howeve...

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Detalles Bibliográficos
Autores principales: Dar, Srishti, Pucadyil, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221619/
https://www.ncbi.nlm.nih.gov/pubmed/28035046
http://dx.doi.org/10.1091/mbc.E16-09-0640