HMGB1 translocation and release mediate cigarette smoke–induced pulmonary inflammation in mice through a TLR4/MyD88-dependent signaling pathway

We performed studies to determine the role of high-mobility group box 1 (HMGB1) in cigarette smoke (CS)–induced pulmonary inflammation. After mice were exposed to five cigarettes four times a day for 3 d, toll-like receptor 4 (TLR4) expression and TLR4-mediated signaling were significantly up-regula...

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Detalles Bibliográficos
Autores principales: Cheng, Yao, Wang, Dan, Wang, Bin, Li, Huanan, Xiong, Junjie, Xu, Shuyun, Chen, Quan, Tao, Kun, Yang, Xiaoyan, Zhu, Yu, He, Sirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221624/
https://www.ncbi.nlm.nih.gov/pubmed/27807045
http://dx.doi.org/10.1091/mbc.E16-02-0126

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