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Model-guided optogenetic study of PKA signaling in budding yeast

In eukaryotes, protein kinase A (PKA) is a master regulator of cell proliferation and survival. The activity of PKA is subject to elaborate control and exhibits complex time dynamics. To probe the quantitative attributes of PKA dynamics in the yeast Saccharomyces cerevisiae, we developed an optogene...

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Detalles Bibliográficos
Autores principales: Stewart-Ornstein, Jacob, Chen, Susan, Bhatnagar, Rajat, Weissman, Jonathan S., El-Samad, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221627/
https://www.ncbi.nlm.nih.gov/pubmed/28035051
http://dx.doi.org/10.1091/mbc.E16-06-0354

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