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Model-guided optogenetic study of PKA signaling in budding yeast
In eukaryotes, protein kinase A (PKA) is a master regulator of cell proliferation and survival. The activity of PKA is subject to elaborate control and exhibits complex time dynamics. To probe the quantitative attributes of PKA dynamics in the yeast Saccharomyces cerevisiae, we developed an optogene...
Autores principales: | Stewart-Ornstein, Jacob, Chen, Susan, Bhatnagar, Rajat, Weissman, Jonathan S., El-Samad, Hana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221627/ https://www.ncbi.nlm.nih.gov/pubmed/28035051 http://dx.doi.org/10.1091/mbc.E16-06-0354 |
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