Whole-Body Distribution of Donepezil as an Acetylcholinesterase Inhibitor after Oral Administration in Normal Human Subjects: A (11)C-donepezil PET Study

OBJECTIVE(S): It is difficult to investigate the whole-body distribution of an orally administered drug by means of positron emission tomography (PET), owing to the short physical half-life of radionuclides, especially when (11)C-labeled compounds are tested. Therefore, we aimed to examine the whole...

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Detalles Bibliográficos
Autores principales: Mochida, Ikuko, Shimosegawa, Eku, Kanai, Yasukazu, Naka, Sadahiro, Matsunaga, Keiko, Isohashi, Kayako, Horitsugi, Genki, Watabe, Tadashi, Kato, Hiroki, Hatazawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Oceania Journal of Nuclear Medicine & Biology 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221682/
https://www.ncbi.nlm.nih.gov/pubmed/28840133
http://dx.doi.org/10.22038/aojnmb.2016.7513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221682/
https://www.ncbi.nlm.nih.gov/pubmed/28840133
http://dx.doi.org/10.22038/aojnmb.2016.7513

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