Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform()

Cardiomyocytes from human pluripotent stem cells (hPSCs-CMs) could revolutionise biomedicine. Global burden of heart failure will soon reach USD $90bn, while unexpected cardiotoxicity underlies 28% of drug withdrawals. Advances in hPSC isolation, Cas9/CRISPR genome engineering and hPSC-CM differenti...

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Detalles Bibliográficos
Autores principales: Denning, Chris, Borgdorff, Viola, Crutchley, James, Firth, Karl S.A., George, Vinoj, Kalra, Spandan, Kondrashov, Alexander, Hoang, Minh Duc, Mosqueira, Diogo, Patel, Asha, Prodanov, Ljupcho, Rajamohan, Divya, Skarnes, William C., Smith, James G.W., Young, Lorraine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221745/
https://www.ncbi.nlm.nih.gov/pubmed/26524115
http://dx.doi.org/10.1016/j.bbamcr.2015.10.014

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