Potential inhibition of HIV-1 encapsidation by oligoribonucleotide–dendrimer nanoparticle complexes

BACKGROUND: Encapsidation, the process during which the genomic RNA of HIV is packaged into viral particles, is an attractive target for antiviral therapy. This study explores a novel nanotechnology-based strategy to inhibit HIV encapsidation by an RNA decoy mechanism. The design of the 16-mer oligo...

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Detalles Bibliográficos
Autores principales: Parboosing, Raveen, Chonco, Louis, de la Mata, Francisco Javier, Govender, Thavendran, Maguire, Glenn EM, Kruger, Hendrik G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221794/
https://www.ncbi.nlm.nih.gov/pubmed/28115849
http://dx.doi.org/10.2147/IJN.S114446

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