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Spatiotemporal coupling and decoupling of gene transcription with DNA replication origins during embryogenesis in C. elegans
The primary task of developing embryos is genome replication, yet how DNA replication is integrated with the profound cellular changes that occur through development is largely unknown. Using an approach to map DNA replication at high resolution in C. elegans, we show that replication origins are ma...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222557/ https://www.ncbi.nlm.nih.gov/pubmed/28009254 http://dx.doi.org/10.7554/eLife.21728 |