Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed to confer protection against Plasmodium falciparum malaria, but the precise nature of the protective effect has proved difficult to define as G6PD deficiency has multiple allelic variants with different effects in males and females, and...

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Detalles Bibliográficos
Autores principales: Clarke, Geraldine M, Rockett, Kirk, Kivinen, Katja, Hubbart, Christina, Jeffreys, Anna E, Rowlands, Kate, Jallow, Muminatou, Conway, David J, Bojang, Kalifa A, Pinder, Margaret, Usen, Stanley, Sisay-Joof, Fatoumatta, Sirugo, Giorgio, Toure, Ousmane, Thera, Mahamadou A, Konate, Salimata, Sissoko, Sibiry, Niangaly, Amadou, Poudiougou, Belco, Mangano, Valentina D, Bougouma, Edith C, Sirima, Sodiomon B, Modiano, David, Amenga-Etego, Lucas N, Ghansah, Anita, Koram, Kwadwo A, Wilson, Michael D, Enimil, Anthony, Evans, Jennifer, Amodu, Olukemi K, Olaniyan, Subulade, Apinjoh, Tobias, Mugri, Regina, Ndi, Andre, Ndila, Carolyne M, Uyoga, Sophie, Macharia, Alexander, Peshu, Norbert, Williams, Thomas N, Manjurano, Alphaxard, Sepúlveda, Nuno, Clark, Taane G, Riley, Eleanor, Drakeley, Chris, Reyburn, Hugh, Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Dunstan, Sarah J, Phu, Nguyen Hoan, Quyen, Nguyen Ngoc, Thai, Cao Quang, Hien, Tran Tinh, Manning, Laurens, Laman, Moses, Siba, Peter, Karunajeewa, Harin, Allen, Steve, Allen, Angela, Davis, Timothy ME, Michon, Pascal, Mueller, Ivo, Molloy, Síle F, Campino, Susana, Kerasidou, Angeliki, Cornelius, Victoria J, Hart, Lee, Shah, Shivang S, Band, Gavin, Spencer, Chris CA, Agbenyega, Tsiri, Achidi, Eric, Doumbo, Ogobara K, Farrar, Jeremy, Marsh, Kevin, Taylor, Terrie, Kwiatkowski, Dominic P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222559/
https://www.ncbi.nlm.nih.gov/pubmed/28067620
http://dx.doi.org/10.7554/eLife.15085

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