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Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. Most of the approaches currently under development involve transplantation of immature progenitors that subsequently undergo phenotypic and functional maturation in vivo, and predicting the long-term graf...

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Detalles Bibliográficos
Autores principales: Kirkeby, Agnete, Nolbrant, Sara, Tiklova, Katarina, Heuer, Andreas, Kee, Nigel, Cardoso, Tiago, Ottosson, Daniella Rylander, Lelos, Mariah J., Rifes, Pedro, Dunnett, Stephen B., Grealish, Shane, Perlmann, Thomas, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222722/
https://www.ncbi.nlm.nih.gov/pubmed/28094017
http://dx.doi.org/10.1016/j.stem.2016.09.004