Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

The integrity of eukaryotic genomes requires rapid and regulated chromatin replication. How this is accomplished is still poorly understood. Using purified yeast replication proteins and fully chromatinized templates, we have reconstituted this process in vitro. We show that chromatin enforces DNA r...

Descripción completa

Detalles Bibliográficos
Autores principales: Kurat, Christoph F., Yeeles, Joseph T.P., Patel, Harshil, Early, Anne, Diffley, John F.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222724/
https://www.ncbi.nlm.nih.gov/pubmed/27989438
http://dx.doi.org/10.1016/j.molcel.2016.11.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222724/
https://www.ncbi.nlm.nih.gov/pubmed/27989438
http://dx.doi.org/10.1016/j.molcel.2016.11.016

Ejemplares similares