How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication

The eukaryotic replisome is a molecular machine that coordinates the Cdc45-MCM-GINS (CMG) replicative DNA helicase with DNA polymerases α, δ, and ε and other proteins to copy the leading- and lagging-strand templates at rates between 1 and 2 kb min(−1). We have now reconstituted this sophisticated m...

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Detalles Bibliográficos
Autores principales: Yeeles, Joseph T.P., Janska, Agnieska, Early, Anne, Diffley, John F.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222725/
https://www.ncbi.nlm.nih.gov/pubmed/27989442
http://dx.doi.org/10.1016/j.molcel.2016.11.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222725/
https://www.ncbi.nlm.nih.gov/pubmed/27989442
http://dx.doi.org/10.1016/j.molcel.2016.11.017

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