Cargando…

Glutamic acid promotes monacolin K production and monacolin K biosynthetic gene cluster expression in Monascus

This study investigated the effects of glutamic acid on production of monacolin K and expression of the monacolin K biosynthetic gene cluster. When Monascus M1 was grown in glutamic medium instead of in the original medium, monacolin K production increased from 48.4 to 215.4 mg l(−1), monacolin K pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Chan, Liang, Jian, Yang, Le, Chai, Shiyuan, Zhang, Chenxi, Sun, Baoguo, Wang, Chengtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222764/ https://www.ncbi.nlm.nih.gov/pubmed/28070827 http://dx.doi.org/10.1186/s13568-016-0311-z

Ejemplares similares

Metabolomics Analysis of the Effect of Glutamic Acid on Monacolin K Synthesis in Monascus purpureus
por: Zhang, Chan, et al.
Publicado: (2020)

Effect of γ-Heptalactone on the Morphology and Production of Monascus Pigments and Monacolin K in Monascus purpureus
por: Shi, Ruoyu, et al.
Publicado: (2022)

De Novo RNA Sequencing and Transcriptome Analysis of Monascus purpureus and Analysis of Key Genes Involved in Monacolin K Biosynthesis
por: Zhang, Chan, et al.
Publicado: (2017)

NaCl Inhibits Citrinin and Stimulates Monascus Pigments and Monacolin K Production
por: Zhen, Zhixin, et al.
Publicado: (2019)

Investigation of monacolin K, yellow pigments, and citrinin production capabilities of Monascus purpureus and Monascus ruber (Monascus pilosus)
por: Lin, Tzu-shing, et al.
Publicado: (2023)

A systematic study of the production of Monacolin K by solid state fermentation of Monascus ruber
por: Liu, Xiuhe, et al.
Publicado: (2022)

Production of Monacolin K in Monascus pilosus: Comparison between Industrial Strains and Analysis of Its Gene Clusters
por: Dai, Weihua, et al.
Publicado: (2021)

Assessment of Monacolin in the Fermented Products Using Monascus purpureus FTC5391
por: Ajdari, Zahra, et al.
Publicado: (2011)

Production of red yeast rice rich in monacolin K by variable temperature solid fermentation of Monascus purpureus
por: Yuan, Xinsong, et al.
Publicado: (2023)

Effects of Chinese medicines on monacolin K production and related genes transcription of Monascus ruber in red mold rice fermentation
por: Peng, Lin, et al.
Publicado: (2020)

Hypocholesterolemic Activity of Monascus Fermented Product in the Absence of Monacolins with Partial Purification for Functional Food Applications
por: Ajdari, Zahra, et al.
Publicado: (2014)

Heterologous Synthesis of Monacolin J by Reconstructing Its Biosynthetic Gene Cluster in Aspergillus niger
por: Zeng, Xu, et al.
Publicado: (2022)

Identification of the high-yield monacolin K strain from Monascus spp. and its submerged fermentation using different medicinal plants
por: Chen, Yu-Pei, et al.
Publicado: (2022)

Correction: Zhen, Z. et al. NaCl Inhibits Citrinin and Stimulates Monascus Pigments and Monacolin K Production. Toxins 2019, 11, 118
por: Zhen, Zhixin, et al.
Publicado: (2019)

Effects of Monacolin K in Nondiabetic Patients with NAFLD: A Pilot Study
por: Da Porto, Andrea, et al.
Publicado: (2023)

Scientific opinion on the safety of monacolins in red yeast rice
por: Younes, Maged, et al.
Publicado: (2018)

The Role of Nutraceutical Supplements, Monacolin K and Astaxanthin, and Diet in Blood Cholesterol Homeostasis in Patients with Myopathy
por: Villano, Ines, et al.
Publicado: (2022)

Analysis of Monacolins and Berberine in Food Supplements for Lipid Control: An Overview of Products Sold on the Italian Market
por: Marcheluzzo, Sara, et al.
Publicado: (2021)

Retrospective analysis of the effects of a highly standardized mixture of Berberis aristata, Silybum marianum, and monacolins K and KA in patients with dyslipidemia
por: Di Pierro, Francesco, et al.
Publicado: (2016)

Retrospective analysis of the effects of a highly standardized mixture of Berberis aristata, Silybum marianum, and monacolins K and KA in diabetic patients with dyslipidemia
por: Di Pierro, Francesco, et al.
Publicado: (2017)

Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia
por: Protic, Olga, et al.
Publicado: (2022)

Telomerase Inhibitory Effects of Red Pigment Rubropunctatin and Statin Monacolin L Isolated from Red Yeast Rice
por: Xu, Baojun, et al.
Publicado: (2017)

Study of the Effects of Monacolin K and Other Constituents of Red Yeast Rice on Obesity, Insulin-Resistance, Hyperlipidemia, and Nonalcoholic Steatohepatitis Using a Mouse Model of Metabolic Syndrome
por: Fujimoto, Makoto, et al.
Publicado: (2012)

Effect of a food supplement containing berberine, monacolin K, hydroxytyrosol and coenzyme Q(10) on lipid levels: a randomized, double-blind, placebo controlled study
por: D’Addato, Sergio, et al.
Publicado: (2017)

Beneficial Metabolic Effect of a Nutraceuticals Combination (Monacolin K, Yeasted Red Rice, Polyphenolic Extract of Annurca Apple and Berberine) on Acquired Hypercholesterolemia: A Prospective Analysis
por: D’Assante, Roberta, et al.
Publicado: (2021)

A marine sponge associated fungal metabolite monacolin X suppresses angiogenesis by down regulating VEGFR2 signaling
por: Nagabhishek, Sirpu Natesh, et al.
Publicado: (2019)

A Novel Statin Compound from Monacolin J Produced Using CYP102A1-Catalyzed Regioselective C-Hydroxylation
por: Cao, Ngoc Tan, et al.
Publicado: (2021)

Effects of a nutraceutical combination of monacolin, γ-oryzanol and γ-aminobutyric acid on lipid profile and C-reactive protein in mice
por: Derosa, Giuseppe, et al.
Publicado: (2018)

Comparative Chemical Profiling and Monacolins Quantification in Red Yeast Rice Dietary Supplements by (1)H-NMR and UHPLC-DAD-MS
por: Hachem, Rabab, et al.
Publicado: (2020)

Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
por: Angelopoulos, Nicholas, et al.
Publicado: (2023)

A Combination of Lactoplantibacillus plantarum Strains CECT7527, CECT7528, and CECT7529 Plus Monacolin K Reduces Blood Cholesterol: Results from a Randomized, Double-Blind, Placebo-Controlled Study
por: Guerrero-Bonmatty, Rafael, et al.
Publicado: (2021)

Enhancing Monascus Pellet Formation for Improved Secondary Metabolite Production
por: Zhang, Xizi, et al.
Publicado: (2023)

Effects of a Combination of Berberis aristata, Silybum marianum and Monacolin on Lipid Profile in Subjects at Low Cardiovascular Risk; A Double-Blind, Randomized, Placebo-Controlled Trial
por: Giuseppe, Derosa, et al.
Publicado: (2017)

Production of Angkak Through Co-Culture of Monascus Purpureus and MONASCUS RUBER
por: Panda, Bibhu Prasad, et al.
Publicado: (2010)

An Integrated Approach to Determine the Boundaries of the Azaphilone Pigment Biosynthetic Gene Cluster of Monascus ruber M7 Grown on Potato Dextrose Agar
por: Liu, Qingpei, et al.
Publicado: (2021)

Diverse Effects of Amino Acids on Monascus Pigments Biosynthesis in Monascus purpureus
por: Yin, Sheng, et al.
Publicado: (2022)

Effect of Exogenous and Endogenous Ectoine on Monascus Development, Metabolism, and Pigment Stability
por: Gong, Pengfei, et al.
Publicado: (2023)

Methionine and S-Adenosylmethionine Regulate Monascus Pigments Biosynthesis in Monascus purpureus
por: Yin, Sheng, et al.
Publicado: (2022)

Divergence of metabolites in three phylogenetically close Monascus species (M. pilosus, M. ruber, and M. purpureus) based on secondary metabolite biosynthetic gene clusters
por: Higa, Yuki, et al.
Publicado: (2020)

Histone Acetyltransferase Rtt109 Regulates Development, Morphogenesis, and Citrinin Biosynthesis in Monascus purpureus
por: Shi, Ruoyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_k1mtf2l1dct5m8qtqerfvkr1vr