68 and FX2149 Attenuate Mutant LRRK2-R1441C-Induced Neural Transport Impairment

Leucine-rich repeat kinase 2 is a large protein with implications in genetic and sporadic causes of Parkinson's disease. The physiological functions of LRRK2 are largely unknown. In this report, we investigated whether LRRK2 alters neural transport using live-cell imaging techniques and human n...

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Detalles Bibliográficos
Autores principales: Thomas, Joseph M., Li, Tianxia, Yang, Wei, Xue, Fengtian, Fishman, Paul S., Smith, Wanli W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222795/
https://www.ncbi.nlm.nih.gov/pubmed/28119604
http://dx.doi.org/10.3389/fnagi.2016.00337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222795/
https://www.ncbi.nlm.nih.gov/pubmed/28119604
http://dx.doi.org/10.3389/fnagi.2016.00337

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