Differential Cultivation of Francisella tularensis Induces Changes in the Immune Response to and Protective Efficacy of Whole Cell-Based Inactivated Vaccines

Francisella tularensis (Ft) is a category A biothreat agent for which there is no Food and Drug Administration-approved vaccine. Ft can survive in a variety of habitats with a remarkable ability to adapt to changing environmental conditions. Furthermore, Ft expresses distinct sets of antigens (Ags)...

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Detalles Bibliográficos
Autores principales: Kumar, Sudeep, Sunagar, Raju, Pham, Giang, Franz, Brian J., Rosa, Sarah J., Hazlett, Karsten R. O., Gosselin, Edmund J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222797/
https://www.ncbi.nlm.nih.gov/pubmed/28119692
http://dx.doi.org/10.3389/fimmu.2016.00677

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