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Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks

Auditory selective attention paradigms are powerful tools for elucidating the various stages of speech processing. This study examined electrocorticographic activation during target detection tasks within and beyond auditory cortex. Subjects were nine neurosurgical patients undergoing chronic invasi...

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Autores principales: Nourski, Kirill V., Steinschneider, Mitchell, Rhone, Ariane E., Howard III, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222875/
https://www.ncbi.nlm.nih.gov/pubmed/28119593
http://dx.doi.org/10.3389/fnhum.2016.00691
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author Nourski, Kirill V.
Steinschneider, Mitchell
Rhone, Ariane E.
Howard III, Matthew A.
author_facet Nourski, Kirill V.
Steinschneider, Mitchell
Rhone, Ariane E.
Howard III, Matthew A.
author_sort Nourski, Kirill V.
collection PubMed
description Auditory selective attention paradigms are powerful tools for elucidating the various stages of speech processing. This study examined electrocorticographic activation during target detection tasks within and beyond auditory cortex. Subjects were nine neurosurgical patients undergoing chronic invasive monitoring for treatment of medically refractory epilepsy. Four subjects had left hemisphere electrode coverage, four had right coverage and one had bilateral coverage. Stimuli were 300 ms complex tones or monosyllabic words, each spoken by a different male or female talker. Subjects were instructed to press a button whenever they heard a target corresponding to a specific stimulus category (e.g., tones, animals, numbers). High gamma (70–150 Hz) activity was simultaneously recorded from Heschl’s gyrus (HG), superior, middle temporal and supramarginal gyri (STG, MTG, SMG), as well as prefrontal cortex (PFC). Data analysis focused on: (1) task effects (non-target words in tone detection vs. semantic categorization task); and (2) target effects (words as target vs. non-target during semantic classification). Responses within posteromedial HG (auditory core cortex) were minimally modulated by task and target. Non-core auditory cortex (anterolateral HG and lateral STG) exhibited sensitivity to task, with a smaller proportion of sites showing target effects. Auditory-related areas (MTG and SMG) and PFC showed both target and, to a lesser extent, task effects, that occurred later than those in the auditory cortex. Significant task and target effects were more prominent in the left hemisphere than in the right. Findings demonstrate a hierarchical organization of speech processing during auditory selective attention.
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spelling pubmed-52228752017-01-24 Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks Nourski, Kirill V. Steinschneider, Mitchell Rhone, Ariane E. Howard III, Matthew A. Front Hum Neurosci Neuroscience Auditory selective attention paradigms are powerful tools for elucidating the various stages of speech processing. This study examined electrocorticographic activation during target detection tasks within and beyond auditory cortex. Subjects were nine neurosurgical patients undergoing chronic invasive monitoring for treatment of medically refractory epilepsy. Four subjects had left hemisphere electrode coverage, four had right coverage and one had bilateral coverage. Stimuli were 300 ms complex tones or monosyllabic words, each spoken by a different male or female talker. Subjects were instructed to press a button whenever they heard a target corresponding to a specific stimulus category (e.g., tones, animals, numbers). High gamma (70–150 Hz) activity was simultaneously recorded from Heschl’s gyrus (HG), superior, middle temporal and supramarginal gyri (STG, MTG, SMG), as well as prefrontal cortex (PFC). Data analysis focused on: (1) task effects (non-target words in tone detection vs. semantic categorization task); and (2) target effects (words as target vs. non-target during semantic classification). Responses within posteromedial HG (auditory core cortex) were minimally modulated by task and target. Non-core auditory cortex (anterolateral HG and lateral STG) exhibited sensitivity to task, with a smaller proportion of sites showing target effects. Auditory-related areas (MTG and SMG) and PFC showed both target and, to a lesser extent, task effects, that occurred later than those in the auditory cortex. Significant task and target effects were more prominent in the left hemisphere than in the right. Findings demonstrate a hierarchical organization of speech processing during auditory selective attention. Frontiers Media S.A. 2017-01-10 /pmc/articles/PMC5222875/ /pubmed/28119593 http://dx.doi.org/10.3389/fnhum.2016.00691 Text en Copyright © 2017 Nourski, Steinschneider, Rhone and Howard. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Nourski, Kirill V.
Steinschneider, Mitchell
Rhone, Ariane E.
Howard III, Matthew A.
Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks
title Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks
title_full Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks
title_fullStr Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks
title_full_unstemmed Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks
title_short Intracranial Electrophysiology of Auditory Selective Attention Associated with Speech Classification Tasks
title_sort intracranial electrophysiology of auditory selective attention associated with speech classification tasks
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222875/
https://www.ncbi.nlm.nih.gov/pubmed/28119593
http://dx.doi.org/10.3389/fnhum.2016.00691
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