Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines

A new method for the preparation of new heterocyclic amine surfactants based on sulfobetaines is proposed. Interfacial activities of the surfactants obtained in aqueous solution were studied by surface tension measurements. The critical micelle concentration, surface excess concentration, minimum ar...

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Autores principales: Wieczorek, Daria, Dobrowolski, Adam, Staszak, Katarzyna, Kwaśniewska, Dobrawa, Dubyk, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222909/
https://www.ncbi.nlm.nih.gov/pubmed/28111518
http://dx.doi.org/10.1007/s11743-016-1906-8
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author Wieczorek, Daria
Dobrowolski, Adam
Staszak, Katarzyna
Kwaśniewska, Dobrawa
Dubyk, Patrycja
author_facet Wieczorek, Daria
Dobrowolski, Adam
Staszak, Katarzyna
Kwaśniewska, Dobrawa
Dubyk, Patrycja
author_sort Wieczorek, Daria
collection PubMed
description A new method for the preparation of new heterocyclic amine surfactants based on sulfobetaines is proposed. Interfacial activities of the surfactants obtained in aqueous solution were studied by surface tension measurements. The critical micelle concentration, surface excess concentration, minimum area per surfactant molecule, and standard Gibbs energy of adsorption were determined. The adsorption properties of these compounds depend significantly on the alkyl chain length. Alkyl chain length also affects biological properties of the new surfactants, determining the minimum inhibitory concentration and size of inhibited growth zone. The compounds have high antimicrobial activity.
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spelling pubmed-52229092017-01-19 Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines Wieczorek, Daria Dobrowolski, Adam Staszak, Katarzyna Kwaśniewska, Dobrawa Dubyk, Patrycja J Surfactants Deterg Original Article A new method for the preparation of new heterocyclic amine surfactants based on sulfobetaines is proposed. Interfacial activities of the surfactants obtained in aqueous solution were studied by surface tension measurements. The critical micelle concentration, surface excess concentration, minimum area per surfactant molecule, and standard Gibbs energy of adsorption were determined. The adsorption properties of these compounds depend significantly on the alkyl chain length. Alkyl chain length also affects biological properties of the new surfactants, determining the minimum inhibitory concentration and size of inhibited growth zone. The compounds have high antimicrobial activity. Springer Berlin Heidelberg 2016-11-15 2017 /pmc/articles/PMC5222909/ /pubmed/28111518 http://dx.doi.org/10.1007/s11743-016-1906-8 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Wieczorek, Daria
Dobrowolski, Adam
Staszak, Katarzyna
Kwaśniewska, Dobrawa
Dubyk, Patrycja
Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines
title Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines
title_full Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines
title_fullStr Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines
title_full_unstemmed Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines
title_short Synthesis, Surface and Antimicrobial Activity of Piperidine-Based Sulfobetaines
title_sort synthesis, surface and antimicrobial activity of piperidine-based sulfobetaines
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222909/
https://www.ncbi.nlm.nih.gov/pubmed/28111518
http://dx.doi.org/10.1007/s11743-016-1906-8
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AT kwasniewskadobrawa synthesissurfaceandantimicrobialactivityofpiperidinebasedsulfobetaines
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