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Early life peripheral lipopolysaccharide challenge reprograms catecholaminergic neurons

Neonatal immune challenge with the bacterial mimetic lipopolysaccharide has the capacity to generate long-term changes in the brain. Neonatal rats were intraperitoneally injected with lipopolysaccharide (0.05 mg/kg) on postnatal day (PND) 3 and again on PND 5. The activation state of tyrosine hydrox...

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Detalles Bibliográficos
Autores principales: Ong, Lin Kooi, Fuller, Erin A., Sominsky, Luba, Hodgson, Deborah M., Dunkley, Peter R., Dickson, Phillip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223129/
https://www.ncbi.nlm.nih.gov/pubmed/28071709
http://dx.doi.org/10.1038/srep40475

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