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Early life peripheral lipopolysaccharide challenge reprograms catecholaminergic neurons
Neonatal immune challenge with the bacterial mimetic lipopolysaccharide has the capacity to generate long-term changes in the brain. Neonatal rats were intraperitoneally injected with lipopolysaccharide (0.05 mg/kg) on postnatal day (PND) 3 and again on PND 5. The activation state of tyrosine hydrox...
Autores principales: | Ong, Lin Kooi, Fuller, Erin A., Sominsky, Luba, Hodgson, Deborah M., Dunkley, Peter R., Dickson, Phillip W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223129/ https://www.ncbi.nlm.nih.gov/pubmed/28071709 http://dx.doi.org/10.1038/srep40475 |
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