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High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss
Epigenetic factors have been suggested to play an important role in metabolic memory by trapping and maintaining initial metabolic changes within the transcriptional regulatory machinery. In this study we fed mice a high fat diet (HFD) for seven weeks followed by additional five weeks of chow, to id...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223143/ https://www.ncbi.nlm.nih.gov/pubmed/28071704 http://dx.doi.org/10.1038/srep40220 |