Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage

Transdifferentiation has been described as a novel method for converting human fibroblasts into induced cardiomyocyte-like cells. Such an approach can produce differentiated cells to study physiology or pathophysiology, examine drug interactions or toxicities, and engineer cardiac tissues. Here we d...

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Detalles Bibliográficos
Autores principales: Christoforou, Nicolas, Chakraborty, Syandan, Kirkton, Robert D., Adler, Andrew F., Addis, Russell C., Leong, Kam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223186/
https://www.ncbi.nlm.nih.gov/pubmed/28071742
http://dx.doi.org/10.1038/srep40285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223186/
https://www.ncbi.nlm.nih.gov/pubmed/28071742
http://dx.doi.org/10.1038/srep40285

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