Plasma heme-induced renal toxicity is related to a capillary rarefaction

Severe hypertension can lead to malignant hypertension (MH) with renal thrombotic microangiopathy and hemolysis. The role of plasma heme release in this setting is unknown. We aimed at evaluating the effect of a mild plasma heme increase by hemin administration in angiotensin II (AngII)-mediated hyp...

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Detalles Bibliográficos
Autores principales: Tabibzadeh, Nahid, Estournet, Céline, Placier, Sandrine, Perez, Joëlle, Bilbault, Héloïse, Girshovich, Alexis, Vandermeersch, Sophie, Jouanneau, Chantal, Letavernier, Emmanuel, Hammoudi, Nadjib, Lionnet, François, Haymann, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223203/
https://www.ncbi.nlm.nih.gov/pubmed/28071761
http://dx.doi.org/10.1038/srep40156

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